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Case Report

Biopsy-Proven Acute Tubular Necrosis Associated with Vancomycin in an Adult Patient

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Pages 502-505 | Received 07 Nov 2011, Accepted 02 Jan 2012, Published online: 14 Feb 2012

Figures & data

Figure 1. The tubular epithelium is flattened, with loss of brush borders and decreased numbers of nuclei. Several tubules show reactive nuclear enlargement with sloughing of cell debris into the tubular lumens.

Figure 1. The tubular epithelium is flattened, with loss of brush borders and decreased numbers of nuclei. Several tubules show reactive nuclear enlargement with sloughing of cell debris into the tubular lumens.

Figure 2. Small foci of interstitial inflammation are present, containing lymphocytes, macrophages, and occasional plasma cells and only rare eosinophils. Several tubules contain a mixture of neutrophils and cell debris (neutrophil casts).

Figure 2. Small foci of interstitial inflammation are present, containing lymphocytes, macrophages, and occasional plasma cells and only rare eosinophils. Several tubules contain a mixture of neutrophils and cell debris (neutrophil casts).

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