Peripheral Arterial Disease Predicts Overall and Cardiovascular Mortality in Peritoneal Dialysis Patients

Figures & data

Figure 1.  Overall mortality between PAD and non-PAD patients by K–M analysis.

Figure 2.  Cardiovascular mortality between PAD and non-PAD patients by K–M analysis.

Table 1.  Causes of death in all patients.

Unknown	1
Cancer	2
Sudden death	4
GI bleeding	3
Peritonitis	4
Pneumonia	4
Cerebral disease	6
Cardiac disease	12

Table 2.  Baseline characteristics between PAD and non-PAD groups.

	PAD	Non-PAD	p
Age (years)	71 ± 6	70 ± 6	0.227
Gender (M%)	52	42	0.235
Aspirin (%)	26	25	0.915
Smoker (%)	37	23	0.091
DM (%)	58	32	0.001
CVD (%)	42	26	0.028
Height (cm)	160 ± 9	159 ± 8	0.852
Weight (kg)	61 ± 13	60 ± 11	0.274
BMI (kg/m^2)	24 ± 3.6	23 ± 3.8	0.278
Dialysis vintage (m)	16 ± 18	15 ± 19	0.756
SBP (mm Hg)	134 ± 28	135 ± 22	0.651
DBP (mm Hg)	72 ± 13	77 ± 12	0.021
CRP	1.7 ± 1.4	1.2 ± 1.6	0.043
Glu (mmol/L)	7 ± 2.9	6.6 ± 2.4	0.283
ALB (g/L)	37.6 ± 4	38.2 ± 4	0.398
Hb (g/L)	114 ± 17	118 ± 16	0.175
HDL (mmol/L)	1 ± 0.3	1 ± 0.3	0.365
TC (mmol/L)	5.4 ± 1.1	5.7 ± 1.6	0.191
TG (mmol/L)	2.8 ± 1.7	3 ± 2	0.538
Total-KT/V	1.87 ± 0.5	1.95 ± 0.6	0.442
Renal-KT/V	0.56 ± 0.7	0.45 ± 0.6	0.249
ABI	0.74 ± 0.34	1.08 ± 0.22	<0.001

Notes: PAD, peripheral arterial disease, CVD, cardiovascular disease; DM, diabetes mellitus; SBP, systolic blood pressure; DBP, diastolic blood pressure; CRP, C-reactive protein; ALB, albumin; HDL, high density lipoprotein; TC, total cholesterol; TG, triglyceride.

Table 3.  Univariate analysis of variables associated with overall and cardiovascular mortality.

	All-cause mortality				CVD mortality
Variables	p	Exp (B)	95% CI		p	Exp (B)	95% CI
PAD	0.014	2.278	1.182	4.389	0.025	2.697	1.134	6.411
Age	0.041	1.058	1.002	1.117	0.346	1.035	0.964	1.111
Renal-KTV	0.045	0.376	0.144	0.980	0.230	0.514	0.173	1.525
Glu	0.039	1.096	1.005	1.196	0.036	1.118	1.007	1.242
ALB	0.000	0.885	0.830	0.943	0.007	0.890	0.819	0.968
Hb	0.080	0.981	0.961	1.002	0.042	0.972	0.947	0.999
CRP	0.078	1.227	0.977	1.541	0.016	1.471	1.076	2.012

Notes: PAD, peripheral arterial disease, CVD, cardiovascular disease; CRP, C-reactive protein; 95% CI, 95% confidence interval.

Table 4.  Multivariate analysis of variables associated with overall and cardiovascular mortality.

	All-cause mortality				CVD mortality
Variables	p	Exp (B)	95% CI		p	Exp (B)	95% CI
PAD	0.023	2.143	1.113	4.129	0.035	2.540	1.069	6.036
ALB	0.000	0.886	0.829	0.946	0.010	0.892	0.817	0.973

Notes: PAD, peripheral arterial disease, CVD, cardiovascular disease; 95% CI, 95% confidence interval.

Liu J-H, Chang C-C, Wang S-M, . Peripheral arterial disease and clinical risks in Taiwanese hemodialysis patients. Angiology. 2010;61(1):66–73.

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