Temporary Peritoneal Dialysis in Newborns and Children: A Single-Center Experience over Five Years

Figures & data

Table 1. Primary diseases of children.

	Inborn metabolic disorders	Sepsis	Sepsis and RDS	Asphyxia	CS	HUS	CKD
Newborn (n = 21) (53.8%)	7 (33.3%)	5 (23.8%)	3 (14.3%)	2 (9.5%)	3 (14.3%)		1(4.8%)
Infant (n = 9) (23.1%)	3 (33.3%)	4 (44.5%)			1 (11.1%)	1(11.1%)
Children (n = 9) (23.1%)	4 (44.5%)	3 (33.3%)			1 (11.1%)	1(11.1%)

Note: RDS, respiratory distress; CS, cardiac surgery; HUS, hemolytic uremic syndrome; CKD, cystic kidney disease.

Table 2. Main indications of PD.

	Fluid overload, hyperkalemia	Fluid overload, hypernatremia	Refractory acidosis	Hyperkalemia
Newborn	13		3 (1 with MD)	5
Infant	3	3	2 (1 with MD)	1
Children	5	1	3 (2 with MD)

Note: MD, metabolic disorder.

Table 3. The mean values of GFR, DPD, BUN, creatinine, and LOS according to gender, age, presence of nephrotoxic agent, maturity, organ failure, and outcome (mean ± standard deviation).

		GFR (mL/min/1.73 m^2)	Duration of PD (day)	BUN (mg/dL)	Creatinine (mg/dL)	LOS (day)
Gender	Male	20.8 ± 3.9	4.64 ± 0.8	55.5 ± 13.2	2.64 ± 0.5	21.5 ± 6.7
	Female	29.7 ± 7.6	4.68 ± 0.8	43.4 ± 11.9	2.35 ± 0.9	20.3 ± 3.7
Age	Newborn	19.9 ± 5.5	3.7 ± 0.7	41.5 ± 10.6	2.23 ± 0.3	18.1 ± 5.9
	Infant	41.2 ± 11.5	4.7 ± 1.2	51.1 ± 25.4	2.58 ± 0.9	26.9 ± 6
	Children	21.5 ± 3.8	7.1 ± 1.4	68.1 ± 10.5	3.11 ± 0.6	21.1 ± 3.9
Nephrotoxic agent	+	23.2 ± 3.7	4.3 ± 0.7	39.1 ± 6.4	1.94 ± 0.3	17.1 ± 3.2
	–	27.8 ± 8.1	5 ± 0.9	59.2 ± 16.3	3.0 ± 0.6	24.7 ± 6.6
Maturity	Premature	10.8 ± 1.3	2.85 ± 0.9	40.5 ± 7.9	1.87 ± 9.1	12.8 ± 4
	Mature	29 ± 5.3	5.1 ± 0.7	51.1 ± 10.7	2.64 ± 0.4	22.8 ± 4.4
Organ failure	Kidney	25.1 ± 3.8	4.1 ± 0.9	34.3 ± 4.9	1.9 ± 0.2	22.1 ± 3.2
	Multiorgan	21.8 ± 3.2	3.3 ± 0.7	94 ± 27.3	4.1 ± 0.8	19.6 ± 2.4
Outcome	Died	22.3 ± 3.1	2.63 ± 0.4	72 ± 13.6	3.9 ± 1.1	9.45 ± 2.7
	Survived	32.7 ± 4	6 ± 0.8	48.5 ± 11.3	2.4 ± 0.7	26.6 ± 5.4

Note: GFR, glomerular filtration rate; DPD, duration of TPD, BUN, blood urea nitrogen; LOS, length of stay.

Table 4. Complications related to TPD and their characteristics.

			Nephrotoxic drug		Age
		Prematurity	+	−	Newborn	Infant	Children	Total
Organ failure	Kidney	8	14	16	14	8	8	30
	Multiorgan	6	4	5	7	1	1	9
Sepsis	+	8	10	8	10	5	3	18
	−	6	8	13	11	4	6	21
Complication	+	3	5	4	5	1	3	9
	−	11	13	17	16	8	6	30
Repositioning	+	3	5	1	4	1	1	6
	−	11	13	20	17	8	8	33
Outcome	Died	7	10	4	10	2	2	14
	Survived	7	8	17	11	7	7	25