Paraoxonase Enzyme Activity Is Enhanced by Zinc Supplementation in Hemodialysis Patients

Figures & data

Table 1. Lipid profile, Apo-AI, Apo-B levels, and PON activity in the treatment group.

	Times of evaluation
	D0 Mean ± SD	D61 Mean ± SD	p
TC (mg/dl)	152.73 ± 31.85	152.63 ± 31.55	0.960
TG (mg/dl)	137.50 ± 66.88	136.83 ± 66.88	0.880
HDL (mg/dl)	33.52 ± 4.12	36.53 ± 3.87	<0.001
LDL (mg/dl)	91.71 ± 26.14	88.73 ± 26.72	0.090
Apo-AI (mg/dl)	88.60 ± 12.43	101.88 ± 13.07	<0.001
Apo-B (mg/dl)	140.64 ± 28.48	136.18 ± 32.73	0.282
PON (IU/L)	83.27 ± 13.40	97.79 ± 11.59	<0.001

Notes: D0, before the intervention; D61, 60 days after intervention; SD, standard deviation; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Apo-AI, apolipoprotein AI; Apo-B, apolipoprotein B; PON, Paraoxonase.

*Paired student t-test was used.

Table 2. Lipid profile, Apo-AI, Apo-B levels, and PON activity in the control group.

	Times of evaluation
	D0	D61
	Mean ± SD	Mean ± SD	p
TC (mg/dl)	158.40 ± 41.57	170.03 ± 42.30	0.009
TG (mg/dl)	142.60 ± 43.02	170.93 ± 78.39	0.019
HDL (mg/dl)	34.86 ± 3.69	34.70 ± 3.33	0.475
LDL (mg/dl)	95.01 ± 37.47	101.14 ± 40.49	0.219
Apo-AI (mg/dl)	94.66 ± 14.90	91.95 ± 11.45	0.264
Apo-B (mg/dl)	133.72 ± 31.59	143.03 ± 31.35	0.001
PON (IU/L)	89.97 ± 39.49	82.13 ± 38.84	0.025

Notes: D0, before the intervention; D61, 60 days after intervention; SD, standard deviation; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Apo-AI, apolipoprotein AI; Apo-B, apolipoprotein B; PON, Paraoxonase.

*Paired student t-test was used.

Table 3. Comparison of the lipid profile, Apo-AI, Apo-B levels, and PON activity between the treatment and control groups.

	Groups
	Treatment	Control
	Mean ± SD	Mean ± SD	p
TC (mg/dl)	152.63 ± 31.55	170.03 ± 42.30	0.076
TG (mg/dl)	136.83 ± 66.88	170.93 ± 78.39	0.056
HDL (mg/dl)	36.53 ± 3.87	34.70 ± 3.33	0.054
LDL (mg/dl)	88.73 ± 26.72	101.14 ± 40.49	0.166
Apo-AI (mg/dl)	101.88 ± 13.07	91.95 ± 11.45	0.003
Apo-B (mg/dl)	136.18 ± 32.73	143.03 ± 31.35	0.411
PON (IU/L)	97.79 ± 11.59	82.13 ± 38.84	0.042

Notes: SD, standard deviation; TC, total cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Apo-AI, apolipoprotein AI; Apo-B, apolipoprotein B; PON, Paraoxonase.

*Independent sample t-test was used.