Intradialytic hypotension is associated with dialytic age in patients on chronic hemodialysis

Figures & data

Table 1. Characteristics of the participants according to the presence of IDH in 10 consecutive hemodialysis sessions.

	Patients with IDH (n = 11) n (%) or mean ± SD	Patients without IDH (n = 57) n (%) or mean ± SD	p
Age (years)	60 ± 18	62 ± 14	0.742
Sex (female)	5 (45%)	20 (35%)	0.517
Charlson comorbidity index score	4 ± 3	3 ± 2	0.296
Hemoglobin (g/dL)	11.8 ± 0.9	11.3 ± 1	0.133
Serum creatinine (mg/dL)	10.1 ± 3.2	10.5 ± 3.2	0.713
Serum albumin (g/dL)	3.8 ± 0.2	3.9 ± 0.3	0.301
Dialysate sodium concentration  (mEq/L)	140 ± 2	139 ± 2	0.089
Blood flow (mL/min)	268 ± 41	278 ± 26	0.281
Interdialytic weight gain (%)^a	4.2 ± 1.3	3.5 ± 1.2	0.126
Use of ACE-Inhibitors or Sartans	6 (54%)	28 (49%)	0.998
Predialysis systolic blood  pressure (mmHg)	128 ± 14	128 ± 13	0.905
Dialytic age (months)	141 ± 113	82 ± 68	0.025

^aExpressed as percentage of the dry weight.

Table 2. Association (odds ratios, OR, and 95% confidence intervals, CI) of IDH with the variables of interest in the multivariable regression model. All the covariates were entered simultaneously into the regression model.

	OR	95% CI	p
Age (years)	0.94	0.87–1.03	0.198
Sex (female)	0.74	0.10–5.12	0.747
Charlson comorbidity index score	1.08	0.65–1.80	0.767
Hemoglobin (g/dL)	2.01	0.79–5.16	0.144
Serum creatinine (mg/dL)	0.88	0.60–1.29	0.513
Serum albumin (g/dL)	0.11	0.01–2.68	0.176
Dialysate sodium concentration (mEq/L)	1.39	0.90–2.14	0.138
Blood flow (mL/min)	0.97	0.94–1.01	0.165
Interdialytic weight gain (%)^a	1.59	0.78–3.23	0.200
Use of ACE-Inhibitors or Sartans	2.92	0.71–11.66	0.129
Predialysis systolic blood pressure (mmHg)	1.07	0.98–1.16	0.152
Dialytic age (months)	1.01	1.01–1.02	0.048

^aExpressed as percentage of the dry weight.

Table 3. Association (B coefficients, and 95% confidence intervals, CI) of intradialytic hypotensive events with the variables of interest in the multivariable regression model. All the covariates were entered simultaneously into the regression model.

	B	95% CI	p
Age (years)	−0.01	−0.02–0.01	0.566
Sex (female)	−0.12	−0.56–0.33	0.598
Charlson comorbidity index score	0.01	−0.08–0.11	0.780
Hemoglobin (g/dL)	0.22	0.03–0.40	0.021
Serum creatinine (mg/dL)	−0.02	−0.10–0.06	0.545
Serum albumin (g/dL)	−0.68	−1.47–0.11	0.092
Dialysate sodium concentration (mEq/L)	0.04	−0.05–0.13	0.399
Blood flow (mL/min)	−0.01	−0.01–0.01	0.211
Interdialytic weight gain (%)^a	0.19	0.03–0.36	0.024
Use of ACE-Inhibitors or Sartans	0.24	−0.06–0.55	0.116
Predialysis systolic blood pressure (mmHg)	0.02	0.01–0.03	0.047
Dialytic age (months)	0.02	0.01–0.05	0.045

^aExpressed as percentage of the dry weight.