Tricho-rhino-phalangeal syndrome in a 13-year-old girl with chronic renal failure and severe growth retardation

Figures & data

Figure 1. Clinical and radiological features of the index patient. (a) Facial appearance of the patient, (b) voiding urethrocystography reveals bilateral vesicoureteral reflux. Congenital dysplasia of the right hip (after surgery) (c) kidney ultrasound scan reveals bilateral hypodysplasia and (d) X-ray shows deformity of the proximal radius.

Table 1. Spectrum of renal/urogenital abnormalities in patients with tricho-rhino-phalangeal syndrome.

Author/ref	TRPS-type	Renal and urogenital abnormality	Remark
Lu et al.4	II	Congenital nephrotic syndrome	Died in neonatal period
Yáñez et al.5	III	Billateral uretrovesical junction obstruction	Progressed to terminal renal failure
Wilson et al.6	II	VUR
Rossi et al.7	I	VUR
Ramos et al.8	II	VUR	Female Prune Belly syndrome
Howell and Wynne-Davies17	?	Hydroureter
Lemke and Pirsig18	?	Megacystis–megaureter syndrome
Braga et al.19	I	Polycystic ovary
Graybeal et al.20	?	Vaginal agenesis, arcuate uterus, hemosalpinx
Tasic et al. (this report)	III	Bilateral renal hypodysplasia, VUR	Progressed to terminal renal failure

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