Familial MPGN – a case series: a clinical description of familial membranoproliferative glomerulonephritis amongst three Irish families

Figures & data

Figure 1. Family Pedigree of Family 1.

Figure 2. Family Pedigree of Family 2.

Figure 3. Family Pedigree of Family 3. “?” denotes suspected, but unconfirmed, kidney disease in this individual. A histological diagnosis was not obtainable.

Table 1. Clinical characteristics of affected individuals.

Family	Patient	Gender	Type of MPGN	Age at diagnosis	Age at RRT initiation	Age at transplant	Recurrence in transplant
1	1A	Female	I	16	21	22 27 38	No histological evidence of recurrence
	1B	Male	NS	18	21	22 31	No histological evidence of recurrence
2	2A	Male	I	22	23	24	No clinical evidence of recurrence
	2B	Male	I	15	17*	17 24	Recurrence in first transplant (biopsy confirmed)
3	3A	Male	II	34	42	45	No clinical evidence of recurrence
	3B	Female	II	53	57*	57	No clinical evidence of recurrence

*Preemptive transplant, RRT = Renal Replacement Therapy.