Figures & data
Figure 1. Comparison of structural changes due to injection HgCl2 and PSO between groups. (A) group 1 treated with corn oil, represents a normal rat kidney. All anatomical structures look normal. The box represents glomerulus (×100), (B) group 2 treated with HgCl2 5 mg/kg, severe tubular necrosis and atrophy is observed. All structures (boxed area) have been extensively damaged (×100), (C) group 3 treated with PSO 0.4 ml/kg, followed by HgCl2 injection, mild necrosis have been seen (×400), (D) group 4 treated with PSO 0.8 ml/kg, followed by HgCl2 injection, minimal necrosis have been seen (×100). Tubular necrosis rate is at low levels in Group 4 and mild level in Group 3 (boxed area).
Figure 2. Effect of pomegranate seed oil on concentration of urinary glucose (A), urinary protein (B), serum creatinine (C), serum urea (D), renal MDA (E) and total thiol contents (F) in different groups of treated animals. All injections were carried out intraperitoneally. PSO was injected 1 h before HgCl2. Data shown as mean ± SEM (n = 6). *p < 0.05 as compared with HgCl2-treated animals.
