Pulmonary hypertension associates with malnutrition and body composition hemodialysis patients

Figures & data

Table 1. Baseline clinical, demographic, and laboratory characteristics of study group.

	Minimum	Maximum	Mean	Std. Deviation
Age	36	95	60.7	15.9
Body weight (kg)	56.8	111.8	70.2	16.0
BMI	16.8	46.8	27.3	5.1
Percent body fat (%)	16.0	47.0	26.6	10.2
Total body water (L)	19.0	54.5	37.3	8.3
25-OH vitamin D (µg/L)	4.1	37.0	13.5	5.8
Calcium (mg/dL)	5.4	11.3	8.8	0.80
Phosphorus (mg/dL)	0.8	10.3	4.7	1.7
PTH (pg/mL)	83.0	524.0	242.3	291.2
Ferritin (ng/mL)	153.6	1344.0	724.7	482.8
Triglyceride (mg/dL)	97.0	390.0	177.4	100.6
Total cholesterol (mg/dL)	107.0	303.0	166.7	42.3
PAP (mmHg)	15	73.0	28.7	12.4
Left ventricular EF (%)	45	77.0	59.4	10.7
Dialysis vintage (months)	21	154.5	49	49.5
Kt/v	1.29	2.2	1.4	0.2
Albumin (g/dL)	2.7	5.2	3.7	2.5
C-reactive protein (mg/L)	4.5	44.1	19.1	25.6
Venous bicarbonate (meq/L)	17.7	25.8	20.8	2.8
Hemoglobin (g/dL)	10.1	14.9	11.5	1.2

Table 2. Clinical, laboratory, and bioimpedance data in groups of HD patients with and without PH.

	PAP ≥35 mmHg	PAP <35 mmHg	p
Number of patients	48 (26.8%)	131 (73.2%)
Age	68.3 ± 14.4	61.3 ± 14.7	0.005
C-reactive protein (mg/L)	18,2 ± 17	16.2 ± 16.8	NS
Body-mass Index (kg/m^2)	25.1 ± 3.9	27.7 ± 5.3	0.048
Percent body fat (%)	19.7 ± 8	28.1 ± 10	0.001
PAP (mmHg)	44.4 ± 11.3	22.5 ± 5.4	0.0001
Total body water (L)	38.6 ± 9.6	37.3 ± 8.2	NS
25-OH vitamin D (µg/L)	14.4 ± 6.4	13.7 ± 5.7	NS
Dry body weight (kg)	66.5 ± 16.6	71.5 ± 16.3	NS
Calcium (mg/dL)	8.8 ± 1.1	8.9 ± 0.6	NS
Phosphorus (mg/dL)	4.6 ± 1.8	4.6 ± 1.6	NS
PTH (pg/mL)	233.9 ± 196.6	211.8 ± 236.5	NS
Ferritin (ng/mL)	717.2 ± 502.1	786.2 ± 488.1	NS
Triglyceride (mg/dL)	147.9 ± 88.5	182.1 ± 97.7	0.03
Total cholesterol (mg/dL)	146.9 ± 34.5	169.5 ± 43.1	0.004
Left ventricular EF (%)	57.2 ± 11.9	60.8 ± 9.9	NS
Dialysis vintage (months)	40 ± 37.2	54.3 ± 52.6	NS
Kt/v	1.38 ± 0.22	1.46 ± 0.23	NS
Albumin (g/dL)	3.37 ± 0.5	3.9 ± 3.3	0.0001
Hemoglobin (g/dL)	11.3 ± 1.3	11.6 ± 1.2	NS
Venous bicarbonate (meq/L)	19.5 ± 3.5	21.2 ± 2.5	NS

Table 3. Binary logistic regression analysis model; effects of different parameters on dependent variable pulmonary hypertension.

	p	Odd’s ratio
Age	0.205	1.032
Percent body fat (%)	0.002	0.874
Triglyceride (mg/dL)	0.119	1.007
Total cholesterol (mg/dL)	0.014	0.972
Albumin (g/dL)	0.036	0.074
Constant	0.016	258807.4

Figure 1. Correlations between PAP (mmHg) and albumin (g/dL), total cholesterol (mg/dL) levels and body fat percent (%).

Figure 2. Comparison of age, body fat percent (%), albumin (g/dL), and total cholesterol (mg/dL) levels between patients with and without PH.