Evaluation of children with steroid-sensitive nephrotic syndrome in terms of allergies

Figures & data

Table 1. Clinical data for children with steroid-sensitive nephrotic syndrome.

	Total NS N (%)	Frequent relapse N (%)	Infrequent relapse N (%)	p
Number of patients	30	7 (23.3)	23 (76.7)	0.025
Gender (M/F)	17/13	1/6	16/7
Age at diagnosis (years)	4.1 ± 2	4.5 ± 2.8	3.9 ± 1.8	NS
Frequency of attack (per year)	2.3 ± 1	3.7 ± 0.4	1.9 ± 0.7	<0.001
Number of patients atopic	11 (36.7)	3 (42.9)	8 (34.8)	NS
Creatinine clearance (mL/min)		107 ± 9	103 ± 7	NS
Blood pressure (mmHg)		95/63	90/60	NS
IgE in remission (IU/mL) median (25–75p)		213 (42–290)	55 (34–185)	NS
Eosinophil in remission (%) Median (25–75p)		2 (2–3)	3 (2–4)	NS

Note: NS: Non significant.

Figure 1. Comparison of serum IgE values during relapse and remission.

Figure 2. Serum IgE levels in patients with steroid-sensitive nephrotic syndrome with or without atopy.

Table 2. Comparison of children with steroid-sensitive nephrotic syndrome with high or normal IgE values during relapse.

	High IgE %	Normal IgE %	p
Gender
Girls	57.9	18.2	0.034
Boys	42.1	81.8
Existence of relapse
Frequent	36.8	0	0.021
Infrequent	63.2	100
Response to steroids
1st week	10.5	81.8	<0.001
2nd week	57.9	18.2
3rd week	31.6	0
Atopy in history of patient and/or family
Yes	36.8	36.4	NS
No	63.2	63.6
Endurance in skin test
None	100	100
Yes	0	0	NS

Note: NS: Non significant.