Lycopene has reduced renal damage histopathologically and biochemically in experimental renal ischemia-reperfusion injury

Figures & data

Figure 1. Placing atraumatic microvascular clamps to the renal pedicle for renal ischemia.

Table 1. Mean ± standard deviation values in blood serum and tissue samples of animals from experimental groups.

	Urea (BUN) (mg/dL)	Creatinine (mg/dL)	Tissue MDA (nmol/mg protein)	Serum MDA (nmol/mL)	Tissue GSH (nmol/mg protein)	Serum GSH (µmol/mL)
Group C	24.81 ± 2.54	0.30 ± 0.03	3.43 ± 0.44	5.41 ± 2.26	37.98 ± 17.01	0.23 ± 0.10
Group L	17.01 ± 4.02	0.27 ± 0.04	2.00 ± 0.41	6.73 ± 2.14	27.25 ± 17.52	0.33 ± 0.13
Group I	48.70 ± 5.40	0.59 ± 0.18	3.96 ± 1.12	10.66 ± 2.45	11.46 ± 7.27	0.28 ± 0.09
Group T	41.35 ± 6.37	0.51 ± 0.11	2.61 ± 1.04	7.45 ± 1.27	13.6 ± 7.93	0.32 ± 0.15

Figure 2. View of brush border in renal tissue in Group C.

Figure 3. Brush border loss, tubular dilatation and tubular vacuolization in renal tissue after Group I.

Table 2. Mean ± SD histopathological evaluation of renal tissues of the animals from experimental groups.

	Tubular vacuolization	Brush border loss	Tubular necrosis	Tubular dilatation
Group C	0 ± 0	0 ± 0	0 ± 0	0 ± 0
Group L	11.66 ± 19.14	0 ± 0	0 ± 0	0.83 ± 2.04
Group I	35.00 ± 25.88	1.16 ± 0.68	0.16 ± 0.40	15.83 ± 6.64
Group T	1.66 ± 4.08	0 ± 0	0 ± 0	0.83 ± 2.04