Ten-year Perplexing Panuveitis Course in a Case with Juvenile Idiopathic Arthritis and a History of Tuberculosis

Figures & data

FIGURE 1. Clinical course of the case presented. (A) Granulomata along the peripheral iridectomy margin (RE) at the age of 24 years. (B) Disseminated chorioretinal punched-out patches (RE) at the age of 24 years. (A) + (B) raised the suspicion of ocular tuberculosis. (C, D) The infrared and fluorescein angiography images disclosed punched-out scars without active leakage (RE). (E) Considerably clearer vitreous opacity with dry chorioretinal scars after 18 months of anti-tubercular treatment at the age of 30 years (RE). (F) Corectopia with anterior capsule fibrosis at the age of 30 years (RE).

TABLE 1. Clinical suspicions of ocular tuberculosis and subsequent workup results.

Age (years)	Clinical profile	Workup result	Comment
24	1. Granulomata along peripheral iridectomy margin 2. Multifocal choroiditis pattern	1. Strongly positive skin tuberculin test 2. Negative AC tap TB-PCR 3. Therapeutic trial	Aggravated iridocyclitis 4 weeks after therapeutic challenge, chemotherapy discontinued
26	Aggravated iridocyclitis	1. Clear lung fields on chest radiograph 2. Negative AC tap TB-PCR	Methotrexate with topical steroid maintenance
28	Intractable iritis with mutton-fat KP	1. Strongly positive skin tuberculin test 2. Positive QuantiFERON 3. Therapeutic trial	Iridocyclitis abated 12 months after anti-TB challenge

AC, anterior chamber; TB-PCR, tuberculosis polymerase chain reaction; KP, keratic precipitate.