Figures & data
Table 1. Composition of nanoemulsion formulae.
Table 2. Particle size, polydispersity index and zeta potential of the selected nanoemulsion formulae.
Figure 1. TEM micrograph of (a) formula N4 taken at magnification of 30 000×; (b) formula N9 taken at magnification of 50 000×.
Figure 2. In vitro release of resveratrol and curcumin from the mucoadhesive nanoemulsion formula N9 in phosphate buffered saline pH 6 containing 2% tween 80.
Figure 3. Ex vivo permeation of resveratrol and curcumin from the nanoemulsion formula N9 through sheep nasal mucosa.
Figure 4. The effect of three months storage of formula N9 on its particle size, zeta potential and DDPH inhibition percentage.
Figure 5. Optical microscopy image of the rat nasal septum, with the administration of formula N9 in the left nostril.
Figure 6. Quantification of the amounts of resveratrol and curcumin reaching the brain following the intranasal administration of the mucoadhesive formula N9.
