Development and Characterization of Rifampicin Loaded Floating Microspheres

Figures & data

Table 1. Micromeritics properties of developed rifampicin microspheres.

Micromeritics properties	Rifampicin microspheres
Angle of repose	41.05° ± 5
Bulk density (g/cm^3)	0.133
Tapped density (g/cm^3)	0.183
Carr's Index (%)	27.32
Hausner's ratio	1.25
% Compressibility Index	27.27

Figure 1. Photomicrograph of developed formulation at magnification 250 X.

Figure 2. Particle size analysis of developed formulation.

Figure 3. Zeta-potential analysis of developed formulation.

Figure 4. Photograph showing the floatability of developed formulation at different time intervals: (A) 1 hrs; (B) 2 hrs; (C) 3 hrs; (D) 4 hrs; (E) 5 hrs; (F) 6 hrs; (G) 7 hrs; (H) 8 hrs.

Figure 5. In-vitro drug release profile of rifampicin loaded floating microspheres.