Assisted reproductive technology outcomes in azoospermic men: 10 years of experience with surgical sperm retrieval

Figures & data

Table I.  Demographic profile of OA‐TESA and OA‐PESA groups.

Variable	Study group
	OA‐TESA	OA‐PESA	p value
No of cycles	103	171	–
Maternal age (years)	34.3 ± 5.8 (24.8–43.1)	33. ± 5.5 (25.9–40.0)	0.1110
Paternal age (years)	46.2 ± 7.5 (44.8–47.6)	47.8 ± 7.7 (46.5–49.0)	0.1020
Number of follicles retrieved	18.9 ± 12.4 (16.6–21.3)	20.2 ± 13.0 (18.2–22.3)	0.5467
Number of oocytes retrieved	14.14 ± 8.8 (7.3–20.7)	13.6 ± 9.2 (8.8–19.2)	0.4628
Rate of intact oocytes after ICSI (%)	90.8 ± 5.8 (85.5–96.5)	92.5 ± 6.5 (87.9–96.1)	0.1541
Number of embryos transferred	3.0 ± 1.5 (2.9–3.6)	2.9 ± 1.5 (2.6–3.1)	0.1300

Values expressed as mean ± SD (confidence interval for the mean), unless otherwise noted.

Table II.  ICSI outcomes from patients with obstructive azoospermia when the injected spem were retrieved from the testicle (TESA) or epididymis (PESA).

Variable	Study group
	OA‐TESA	OA‐PESA	p value
Normal fertilization rate (%)	57.9 ± 9.5 (48.5–67.5)	65.2 ± 4.1 (54.7–69.3)	0.0017
Abnormal fertilization rate (%)	13.2 ± 6.3 (6.5–19.5)	12.7 ± 5.3 (7.9–18.0)	0.9437
Fertilization failure rate (%)	28.9 ± 8.9 (20.2–37.8)	22.1 ± 6.0 (15.8–28.1)	0.1081
Non‐cleaved rate (%)	9.87 ± 5.9 (4.2–15.8)	7.46 ± 3.9 (3.5–11.4)	0.4406
Pregnancy rate (%)	31.9 ± 9.0 (23.0–41.0)	32.5 ± 7.5 (25.9–40.0)	0.8803
Abortion rate (%)	38.8 ± 9.6 (29.6–48.4)	18.0 ± 5.8 (12.2–23.8)	0.0387
Implantation rate (%)	9.4 ± 5.6 (3.8–15.0)	10.5 ± 4.0 (5.5–14.5)	0.6054

Values in percentage expressed as mean ± SD (confidence interval of the frequencies).

Italicized numbers represent statistically significant differences.

Table III.  Demographic profile of OA‐TESA and NOA‐TESA groups.

Variable	Study group
	OA‐TESA	NOA‐TESA	p value
No of cycles	103	102	–
Maternal age (years)	34.3 ± 5.8 (24.8–43.1)	33.4 ± 5.5 (23.9–42.1)	0.2784
Paternal age (years)	46.2 ± 7.5 (44.8–47.6)	45.8 ± 7.0 (33.6–55.8)	0.1250
Number of follicles retrieved	18.9 ± 12.4 (16.6–21.3)	18.3 ± 11.8 (10.5–25.5)	0.7199
Number of oocytes retrieved	14.14 ± 8.8 (7.3–20.7)	13.6 ± 7.0 (7.3–20.7)	0.5783
Rate of intact oocytes after ICSI (%)	90.8 ± 5.8 (85.5–96.5)	89.8 ± 6.2 (84.2–95.8)	0.9168
Number of embryos transferred	3.0 ± 1.5 (2.9–3.6)	2.9 ± 1.4 (2.6–3.2)	0.8000

Values expressed as mean ± SD (confidence interval for the mean), unless otherwise noted.

Table IV.  ICSI outcomes when the injected sperm were retrieved from the testicle (TESA) of patients with obstructive (OA) or non‐obstructive (NOA) azoospermia.

Variable	Study group
	OA‐TESA	NOA‐TESA	p value
Normal fertilization rate (%)	57.9 ± 9.5 (48.5–67.5)	50.4 ± 9.3 (40.3–59.7)	0.0050
Abnormal fertilization rate (%)	13.2 ± 6.3 (6.5–19.5)	13.98 ± 6.8 (7.3–20.7)	0.4421
Fertilization failure rate (%)	28.9 ± 8.9 (20.2–37.8)	35.65 ± 11.8 (27.6–47.4)	0.0023
Non cleaved rate (%)	9.87 ± 5.9 (4.2–15.8)	16.1 ± 17 (8.9–23.1)	0.0034
Pregnancy rate (%)	31.9 ± 9.0 (23.0–41.0)	29.7 ± 9.2 (21.1–38.9)	0.4166
Abortion rate (%)	38.8 ± 9.6 (29.6–48.4)	37.0 ± 9.4 (27.6–46.4)	0.9992
Implantation rate (%)	9.4 ± 5.6 (3.8–15.0)	9.65 ± 6.1 (4.2–15.8)	0.8519

Values in percentage expressed as mean ± SD (confidence interval of the frequencies).

Italicized numbers represent statistically significant differences.