Plant-derived alternative treatments for the aging male: facts and myths

Figures & data

Figure 1.  Ligand binding assays with recombinant human ERα (upper panel) and ERβ (lower panel) protein. Note the much lower (∼10²–10³) affinity of the phytoestrogens to both receptor subtypes. They have however, a slightly higher affinity to the ERβ protein.

Figure 2.  Effect of a 3 months lasting treatment of orx rats with estradiol (E2), testosterone (T) or genistein (Gen) on cancellous density of the metaphysis of the tibia. Within the 3 months following orx rats lost ∼30% of their cancellous density and this was partially prevented by E2, T or Gen.

Figure 3.  Effects of 2 concentrations of genistein (Gen) on basal proliferation (Figure 3a) or DHT stimulated proliferation (Figure 3b) of LNCaP cells. Figure 3c depicts serum PSA levels in the culture medium.