The impact of metabolic syndrome on serum total testosterone level in patients with erectile dysfunction

Figures & data

Table 1. Principal characteristics of the study population.

	Group 1	Group 2	p Value
Age	54.7 ± 7.9	56.4 ± 8.3	0.099*
WC (cm)	105.0 ± 7.3	90.9 ± 8.8	<0.001^┴
FBG (mg/dL)	161.5 ± 75.0	133.5 ± 88.5	<0.001^┴
BMI (kg/m^2)	30.6 ± 4.4	27 ± 3.7	<0.001*
WHR (cm)	1.00 ± 0.06	0.95 ± 0.07	<0.001^┴
HDL (mg/dL)	40.1 ± 11.1	44.1 ± 15.6	<0.001^┴
TG (mg/dL)	218.6 ± 125.1	154.2 ± 95.5	<0.001^┴
Systolic BP (mmHg)	126.4 ± 23.2	116.9 ± 19.5	<0.001^┴
Diastolic BP (mmHg)	84.7 ± 12.7	77.5 ± 10.3	<0.001^┴
IIEF-EF score	9.4 ± 7.4	12.2 ± 8.0	<0.002^┴
TT (ng/mL)	4.4 ± 1.4	5.3 ± 1.9	<0.001^┴

Independent sample t test*, Mann–Whitney test^┴

Variables are given as means  ±  Standard Deviation.

Abbreviation: WC = Waist circumference; FBG = Fasting blood glucose; BMI = Body Mass Index; WHR = Waist-Hip ratio; HDL = High-density lipoprotein; TG = Triglyceride; BP = Blood Pressure; IIEF-EF, erectile function domain of the International Index of Erectile Function. TT= Total testosterone (2.4–9.5 ng/mL).

Figure 1. Relationship among IIEF-EF, serum TT levels and presence of MetS and/or Hypogonadism.

Table 2. Logistic regression analysis of metabolic risk factors for erectile dysfunction.

	Beta Coefficient	p Value	O.R.	95% CI (Min-Max)
Age	0.068	0.003	1.1	1.0–1.1
Smoking	0.365	0.249	1.4	0.8–2.7
Abnormal WC	−0.318	0.330	0.7	0.4–1.4
Abnormal FBG	2.371	<0.001	10.7	5.1–22.5
Abnormal HDL	−0.182	0.574	0.8	0.4–1.6
Abnormal TG	0.161	0.614	1.2	0.6–2.2
Abnormal BP	0.311	0.371	1.4	0.7–2.7
Presence of Hypogonadism	0.160	0.706	1.2	0.5–2.7

Variables entered as categorical variables, except for age.

Abbreviation: O.R.: Odds ratio CI: confidence interval; WC: waist circumference; FBG; fasting blood glucose; HDL: high-density Lipoprotein; TG: triglyceride; BP: blood pressure