Abstract
Medical therapy for pythiosis is hampered by a lack of efficacious drugs. The present report describes a case of canine gastrointestinal pythiosis in which lesions were resolved through the administration of itraconazole, terbinafine, and the agricultural fungicide mefenoxam. No substantial adverse effects occurred in association with administration of the latter compound. Additional studies are needed to evaluate the pharmacokinetics of mefenoxam and to further assess its tolerability and potential efficacy for the treatment of pythiosis in dogs.
Acknowledgments
We are grateful to Mark Papich, DVM, Roxanne Taylor, DVM, Lindsay Fischer, PharmD, Katie Young, PharmD, and Valerie Coleman, PharmD for their contributions to this case report.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
This paper was first published online on Early Online on 27 December 2010.