1,278
Views
12
CrossRef citations to date
0
Altmetric
Original Article

Restoration of acetylcholinesterase activity by Euphorbia hirta in discrete brain regions of chronically stressed rats

, , , &
Pages 499-503 | Received 02 Oct 2008, Accepted 02 Mar 2009, Published online: 19 Apr 2010

Figures & data

Figure 1. Restoration of CIS-induced increase in AChE activity in the frontal cortex (A), hippocampus (B), and septum (C) by Euphorbia hirta treatment. NC, normal control; CIS, rats subjected to 10 days of chronic immobilization stress; CIS + Veh, CIS + Eh, rats subjected to CIS followed by vehicle or Euphorbia hirta 200 mg/kg, p.o. treatment, respectively. Values represent mean ± SEM. #p < 0.05, ##p < 0.01, ###p < 0.001 vs. NC; **p < 0.01, ***p < 0.001 vs. CIS; one-way ANOVA followed by Tukey’s post hoc test.

Figure 1.  Restoration of CIS-induced increase in AChE activity in the frontal cortex (A), hippocampus (B), and septum (C) by Euphorbia hirta treatment. NC, normal control; CIS, rats subjected to 10 days of chronic immobilization stress; CIS + Veh, CIS + Eh, rats subjected to CIS followed by vehicle or Euphorbia hirta 200 mg/kg, p.o. treatment, respectively. Values represent mean ± SEM. #p < 0.05, ##p < 0.01, ###p < 0.001 vs. NC; **p < 0.01, ***p < 0.001 vs. CIS; one-way ANOVA followed by Tukey’s post hoc test.

Figure 2. Effect of FSS and Eh treatment on AChE activity in the frontal cortex (A), hippocampus (B), and septum (C). NC, normal control; FSS, rats subjected to forced swim stress; FSS + Veh, rats subjected to forced swim stress and vehicle treatment; FSS + Eh, rats subjected to forced swim stress and Euphorbia hirta treatment. Values represent mean ± SEM. #p < 0.05 vs. NC; one-way ANOVA followed by Tukey’s post hoc test.

Figure 2.  Effect of FSS and Eh treatment on AChE activity in the frontal cortex (A), hippocampus (B), and septum (C). NC, normal control; FSS, rats subjected to forced swim stress; FSS + Veh, rats subjected to forced swim stress and vehicle treatment; FSS + Eh, rats subjected to forced swim stress and Euphorbia hirta treatment. Values represent mean ± SEM. #p < 0.05 vs. NC; one-way ANOVA followed by Tukey’s post hoc test.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.