Effect of Hemidesmus indicus on ischemia–reperfusion injury in the isolated rat heart

Figures & data

Table 1.  Effect of Hemidesmus indicus (HI) on post-ischemic functional recovery, reperfusion arrhythmias, and infarct size in the isolated rat heart.

Parameter	C	HI
LVEDP (mm Hg)	80.7 ± 2.1	71 ± 1.8**
+dP/dtmax (% of pre-ischemic value)	9.9 ± 1.4	25.4 ± 6.9*
CF (% of pre-ischemic value)	55.2 ± 7.1	85.0 ± 19.1
VPB (total number)	1728 ± 44.1	877.5 ± 54.7**
Duration of VT (s)	97 ± 14.8	38.5 ± 5.2**
IA/AR (%)	52.6 ± 4.8	43.2 ± 3.7

Note. LVEDP, left ventricular end-diastolic pressure at 40 min of R; +dP/dt_max, maximal rate of pressure development; CF, coronary flow; VPB, ventricular premature beats; VT, ventricular tachycardia; IA, infarct area; AR, area at risk. Data are mean ± SEM (n = 7 per group). *p < 0.05, **p < 0.01 vs. C.

Figure 1.  Effect of Hemidesmus indicus (HI) on post-ischemic recovery of left ventricular developed pressure (LVdevP). C, control non-treated group; HI, HI-treated group. Data are mean ± SEM (n = 7 per group). *p < 0.05, **p < 0.01 vs. C.