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Research Article

Antinociceptive effect of methanol extract of Capparis ovata in mice

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Pages 1185-1190 | Received 29 May 2009, Accepted 16 Jan 2010, Published online: 07 Sep 2010

Figures & data

Figure 1. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on tail-immersion test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; cP < 0.001, significant difference from morphine alone; fP < 0.01, significant difference from CME 200 mg/kg alone.

Figure 1.  The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on tail-immersion test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; cP < 0.001, significant difference from morphine alone; fP < 0.01, significant difference from CME 200 mg/kg alone.

Figure 2. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on the hot-plate test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; bP < 0.001, significant difference from dipyrone; cP < 0.001, significant difference from morphine alone; dP < 0.001, significant difference from CME 50 mg/kg alone; eP < 0.001, significant difference from CME 100 mg/kg alone, fP < 0.001, significant difference from CME 200 mg/kg alone.

Figure 2.  The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on the hot-plate test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; bP < 0.001, significant difference from dipyrone; cP < 0.001, significant difference from morphine alone; dP < 0.001, significant difference from CME 50 mg/kg alone; eP < 0.001, significant difference from CME 100 mg/kg alone, fP < 0.001, significant difference from CME 200 mg/kg alone.

Figure 3. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on acetic acid-induced writhing test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control, cP < 0.001, significant difference from morphine alone.

Figure 3.  The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on acetic acid-induced writhing test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control, cP < 0.001, significant difference from morphine alone.

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