Figures & data
Table 1. Phytochemical screening of Pergularia daemia root extracts (PdAE and PdEE).
Table 2. Effect of PdAE and PdEE on serum enzyme and biochemical parameters in paracetamol-induced hepatotoxicity in rats.
Table 3. Effect of PdAE and PdEE on liver weight, glutathione (GSH) and lipid peroxidation (LPO) in paracetamol-induced hepatotoxicity in rats.
Table 4. Effect of PdAE and PdEE on serum enzyme and biochemical parameters in CCL4-induced hepatotoxicity in rats.
Table 5. Effect of PdAE and PdEE on liver weight, glutathione (GSH) and lipid peroxidation (LPO) in CCL4-induced hepatotoxicity in rats.
Figure 1. Liver section of control rats showing normal hepatic cells.
Figure 2. Liver section of paracetamol rats shows necrosis, ballooning degeneration and massive infiltration of lymphocytes.
Figure 3. Liver section of silymarin and paracetamol rats shows moderate necrosis, moderate ballooning degeneration and little infiltration of lymphocytesries.
Figure 4. Liver section of PdAE (200 mg/kg) and paracetamol showing less fatty changes, mild necrosis, degeneration and little infiltration of lymphocytes.
Figure 5. Liver section of PdEE (200 mg/kg) and paracetamol showing moderate fatty changes, necrosis, ballooning degeneration and no infiltration of lymphocytes.
Figure 6. Liver section of CCl4 rats showing fatty changes, necrosis and filtration of lymphocytes.
Figure 7. Liver section of silymarin and CCl4shows mild fatty changes, necrosis, mild ballooning degeneration and mild infiltration of lymphocytes.
Figure 8. Liver section of PdAE (200 mg/kg) and CCl4 shows mild fatty changes, necrosis, mild ballooning with degeneration and mild infiltration of lymphocytes.
Figure 9. Liver section of PdEE (200 mg/kg) and CCl4 shows fatty changes necrosis, ballooning degeneration and few infiltrations of lymphocytes.
