Wound healing activity of Withania coagulans in streptozotocin-induced diabetic rats

Figures & data

Table 1.  Quantification of withaferin-A in methanolic extract of Withania coagulans by HPTLC.

Sample	Concentration	Volume	Results(mg/g of extract)
Withaferin-A	0.2 mg/mL	8 µL	-
Methanolic extract	4.0 mg/mL	10 µL	3.67

Figure 1.  Peak area for withaferin-A in methanolic extract of Withania coagulans.

Figure 2.  Images of wounds on topical and oral treatment of hydroalcoholic fraction (A) and its effect on wound contraction (B). Group I: normal control, Group II: diabetic control, Group III: diabetic treated with Aloe vera and Group IV: diabetic treated with hydroalcoholic fraction of Withania coagulans.

Figure 3.  Effect of topical and oral treatment of hydroalcoholic fraction on collagen (A) and hexosamine (B) content.

Figure 4.  Effect of topical and oral treatment of hydroalcoholic fraction on protein (A) and DNA (B) content.

Figure 5.  Effect of topical and oral treatment of hydroalcoholic fraction on SOD (A) and catalase (B) level.