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Research Article

Antimutagenic activity of two medicinal phytoextracts in somatic cells of Drosophila melanogaster

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Pages 640-647 | Received 24 Feb 2010, Accepted 24 Sep 2010, Published online: 11 Mar 2011

Figures & data

Figure 1.  UV-HPLC at 254 nm of Cecropia obtusifolia (1) chlorogenic acid and (2) isoorietin.

Figure 1.  UV-HPLC at 254 nm of Cecropia obtusifolia (1) chlorogenic acid and (2) isoorietin.

Figure 2.  UV-HPLC at 254 nm of Equisetum myriochaetum: (1) kaempferol-3-O-sophoroside and (2) kaempferol-3,7-di-O-β-glucoside.

Figure 2.  UV-HPLC at 254 nm of Equisetum myriochaetum: (1) kaempferol-3-O-sophoroside and (2) kaempferol-3,7-di-O-β-glucoside.

Table 1.  Frequency and number of spots/wing obtained after chronic exposure of trans-heterozygous larvae of Drosophila melanogaster to different concentrations of the phytoextracts tested.

Table 2.  Fly spot data obtained after chronic exposure of trans-heterozygous larvae of Drosophila melanogaster to different concentrations of hydrogen peroxide.

Table 3.  Effect of the phytoextracts on the genotoxicity of hydrogen peroxide in the pretreatment protocol.

Figure 3.  Catalase-specific activity in third instar Drosophila melanogaster larvae treated or not with 0.2 M hydrogen peroxide. Data are expressed as nanomoles of oxidized hydrogen peroxide/min/mg of total protein. (A) Standard cross; (B) high-bioactivation cross. *P < 0.05.

Figure 3.  Catalase-specific activity in third instar Drosophila melanogaster larvae treated or not with 0.2 M hydrogen peroxide. Data are expressed as nanomoles of oxidized hydrogen peroxide/min/mg of total protein. (A) Standard cross; (B) high-bioactivation cross. *P < 0.05.

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