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Research Article

Gut modulatory effects of Daphne oleoides are mediated through cholinergic and Ca++ antagonist mechanisms

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Pages 821-825 | Received 26 Oct 2010, Accepted 18 Dec 2010, Published online: 18 Apr 2011

Figures & data

Figure 1.  Concentration-response curves of the crude extract of Daphne oleoides (Do.Cr) on spontaneous contractions of isolated rabbit jejunum preparations in the absence and presence of atropine (0.3 µM). The spasmogenic responses are expressed as percent of the acetylcholine maximum (ACh Max.). Values shown are mean ± SEM, n = 3.

Figure 1.  Concentration-response curves of the crude extract of Daphne oleoides (Do.Cr) on spontaneous contractions of isolated rabbit jejunum preparations in the absence and presence of atropine (0.3 µM). The spasmogenic responses are expressed as percent of the acetylcholine maximum (ACh Max.). Values shown are mean ± SEM, n = 3.

Figure 2.  Concentration-dependent inhibitory effect of Do.Cr and verapamil against high K+-induced contractions in isolated rabbit jejunum preparations. Values shown are mean ± SEM, n = 3.

Figure 2.  Concentration-dependent inhibitory effect of Do.Cr and verapamil against high K+-induced contractions in isolated rabbit jejunum preparations. Values shown are mean ± SEM, n = 3.

Figure 3.  Concentration-response curves of Ca++ in the absence and presence of different concentrations of (A) Do.Cr and (B) verapamil in isolated rabbit jejunum preparations. Values shown are mean ± SEM, n = 3–4.

Figure 3.  Concentration-response curves of Ca++ in the absence and presence of different concentrations of (A) Do.Cr and (B) verapamil in isolated rabbit jejunum preparations. Values shown are mean ± SEM, n = 3–4.

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