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Research Article

Anti-inflammatory, free radical-scavenging, and metal-chelating activities of Malva parviflora

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Pages 942-946 | Received 23 Jun 2010, Accepted 23 Jan 2011, Published online: 19 May 2011

Figures & data

Figure 1.  Effect of M. parviflora leaf extracts on ear edema induced by croton oil. Mice were treated with 0.5 mg/ear of indomethacin (IND), 2 mg/ear of methanol extract (Met. E), and 2 mg/ear of aqueous extract (Aq. E). Control group received croton oil solution only. Edema is expressed as mean thickness increase of ears before and 6 h after croton oil application. Values are expressed as means ± SEM (n = 7). ***P < 0.001. NS: not significant versus the control.

Figure 1.  Effect of M. parviflora leaf extracts on ear edema induced by croton oil. Mice were treated with 0.5 mg/ear of indomethacin (IND), 2 mg/ear of methanol extract (Met. E), and 2 mg/ear of aqueous extract (Aq. E). Control group received croton oil solution only. Edema is expressed as mean thickness increase of ears before and 6 h after croton oil application. Values are expressed as means ± SEM (n = 7). ***P < 0.001. NS: not significant versus the control.

Figure 2.  Effect of M. parviflora leaf extracts on acetic acid-induced vascular permeability. Mice were treated orally with 50 mg/kg of indomethacin (IND), 500 mg/kg of methanol extract (Met. E), and 360 mg/kg of aqueous extract (Aq. E). Control group received 0.2 mL of normal saline solution. Values are expressed as means ± SEM (n = 7). ***P < 0.001. NS: not significant versus the control.

Figure 2.  Effect of M. parviflora leaf extracts on acetic acid-induced vascular permeability. Mice were treated orally with 50 mg/kg of indomethacin (IND), 500 mg/kg of methanol extract (Met. E), and 360 mg/kg of aqueous extract (Aq. E). Control group received 0.2 mL of normal saline solution. Values are expressed as means ± SEM (n = 7). ***P < 0.001. NS: not significant versus the control.

Figure 3.  DPPH radical-scavenging activity of methanol extract (A) and aqueous extract (B) of M. parviflora leaves, and standard antioxidant butylated hydroxytoluene (BHT) (C). Values are expressed as means ± SD (triplicate).

Figure 3.  DPPH radical-scavenging activity of methanol extract (A) and aqueous extract (B) of M. parviflora leaves, and standard antioxidant butylated hydroxytoluene (BHT) (C). Values are expressed as means ± SD (triplicate).

Figure 4.  Ferrous ion chelating activity of methanol extract (A) and aqueous extract (B) of M. parviflora leaves and the standard chelator ethylenediaminetetraacetic acid (EDTA) (C). Values are expressed as means ± SD (triplicate).

Figure 4.  Ferrous ion chelating activity of methanol extract (A) and aqueous extract (B) of M. parviflora leaves and the standard chelator ethylenediaminetetraacetic acid (EDTA) (C). Values are expressed as means ± SD (triplicate).

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