Figures & data
Figure 1. Molecular weight distribution of different forms of MPSP on SDS-PAGE. Lane 1: Low-range marker; lane 2: BSA; lane 3: Phosphorylated MPSP; lane 4: Acetylated MPSP; lane 5: Esterified MPSP; lane 6: Crude MPSP.
Figure 2. The changes in serum total sialic acid (TSA) in the Normal, CPA, CPA + CMPSP, CPA + PMPSP, CPA + AMPSP and CPA + EMPSP groups. Data are expressed as means ± SEM, n = 9. #p < 0.05 and ###p < 0.001 represent significant differences when comparing the serum TSA before and after drug treatment in each group. *p < 0.05 represents significant differences when comparing various treatment groups’ post-treatment serum TSA with that of the CPA + CMPSP. NS refers to no significant difference.
Figure 3. Growth inhibitory effects of crude (A), phosphorylated (B), acetylated (C) and esterified (D) MPSP on C6 and normal brain cells after a 24-h treatment. A graph highlighting the growth inhibitory effects of various forms of MPSP at 100 µg/mL (E). Data are expressed as mean ± SEM, n = 3. *p < 0.05, **p < 0.01, and ***p < 0.001 represent significant differences when comparing with its corresponding concentration in the normal brain cells. #p < 0.05 represents significant differences when comparing the growth inhibitory effects of various forms of MPSP with that of the crude MPSP. NS refers to no significant difference.
