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Original Article

Platelet-activating factor (PAF) receptor binding activity of the roots of Enicosanthellum pulchrum

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Pages 284-290 | Received 16 Jan 2011, Accepted 22 Jun 2011, Published online: 21 Nov 2011

Figures & data

Figure 1.  Isolation scheme for compounds 1, 2, 3, and 4.

Figure 1.  Isolation scheme for compounds 1, 2, 3, and 4.

Figure 2.  Inhibitory effect of the hexane, ethyl acetate and methanol extracts of the roots of E. pulchrum on the PAF receptor binding to rabbit platelets at 18.2 μg mL−1. F(3, 4) = 24.202, p < 0.05. *No significant difference as compared with cedrol.

Figure 2.  Inhibitory effect of the hexane, ethyl acetate and methanol extracts of the roots of E. pulchrum on the PAF receptor binding to rabbit platelets at 18.2 μg mL−1. F(3, 4) = 24.202, p < 0.05. *No significant difference as compared with cedrol.

Figure 3.  Inhibitory effect of the VLC fractions of the ethyl acetate extract from E. pulchrum on the PAF receptor binding to rabbit platelets at 18.2 μg mL−1. F(6, 7) = 19.505, p < 0.05. *No significant difference as compared with cedrol.

Figure 3.  Inhibitory effect of the VLC fractions of the ethyl acetate extract from E. pulchrum on the PAF receptor binding to rabbit platelets at 18.2 μg mL−1. F(6, 7) = 19.505, p < 0.05. *No significant difference as compared with cedrol.

Figure 4.  Structures of compounds 14.

Figure 4.  Structures of compounds 1–4.

Table 1.  1H-NMR and 13C-NMR spectral data of compound 1, 2, 3 and 4.

Table 2.  Inhibitory effects of compounds 1, 3, and 4 on the PAF receptor binding to rabbit platelets at various concentrations.

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