Relaxant effect induced by wogonin from Scutellaria baicalensis on rat isolated uterine smooth muscle

Figures & data

Figure 1.  Chemical structure of wogonin. Molecular formula: C₁₆H₁₂O₅; molecular weight: 284.26.

Figure 2.  Effect of wogonin on the spontaneous contractions in uterine smooth muscle strips isolated from non-pregnant rats. Data are expressed as the mean ± SE (n = 4). *Significantly different from the control (**p < 0.01).

Figure 3.  Effects of wogonin on contractions of rat uterus induced by OXT (0.01 U/ml), PGF_2α (0.1 μM) or ACh (1 μM). Data are expressed as the mean ± SE (n = 4).*Significantly different from the control (**p < 0.01).

Figure 4.  Effects of wogonin on contractions of rat uterus induced by OXT (0.01 U/ml) on Ca²⁺-free solution. Data are expressed as the mean ± SE (n = 4). *Significantly different from the control (**p < 0.01).

Figure 5.  Effects of wogonin on tonic contractions of rat uterus induced by KCl (56.3 mM). Data are expressed as the mean ± SE (n = 4). *Significantly different from the control (**p < 0.01).

Figure 6.  Effect of the potassium channel inhibitors, TEA (1 mM), 4-AP (5 mM), and Glib (30 μM) on wogonin-induced uterine relaxation. Data are expressed as the mean ± SE (n = 4). *Significantly different from the control (*p < 0.05, **p < 0.01).