Sedative effects of essential oils obtained from Baccharis uncinella

Figures & data

Table 1.  Relative compositions of volatile components of the two essential oils samples of Baccharis uncinella collected near (BU-SC) or far (BU-PR) from the Laklaño reservation.

Component	BU-SC %	BU-PR %	RI*
α-thujene	2.91		932
α-pinene	6.42		940
β-pinene	3.68		980
limonene	7.21		1032
terpinen-4-ol		0.31	1180
α-copaene	2.93	0.27	1376
β-cubebene		0.32	1391
β-elemene		0.22	1393
β-caryophyllene	26.13	0.92	1419
aromadendrene		0.51	1440
α-caryophyllene	3.63		1456
γ-gurjunene		1.81	1472
β-chamigrene		0.25	1476
germacrene D	1.88	t	1480
α-muurolene		1.34	1499
γ-cadinene		2.30	1510
β-cadinene	4.06	0.44	1522
trans-calamenene		0.56	1529
α-calacorene		2.23	1550
spathulenol	13.39	32.93	1578
caryophyllene oxide	13.26	27.78	1583
viridiflorol	t	5.29	1590
α-cadinol	t	2.42	1654
Sample yielding (w/w, %)	0.86	0.80
Total identified (%)	85.50	79.90
Monoterpenes (%)	20.22	0.31
Sesquiterpenes (%)	65.28	79.59
Monoterpene/Sesquiterpene	0.310	0.004

*RI: mean of the retention indices of each component.

t: trace amount, below 0.10%.

Figure 1.  Effects of Baccharis uncinella essential oils (BU-PR and BU-SC, 50 and 100 mg/kg, i.p.) on pentobarbital-induced sleep in mice. Diazepam 2 mg/kg was used as positive control. Each column represent the mean ± S.E.M. (n = 8–10). * = p < 0.05; ** = p < 0.01 vs. control ANOVA/SNK.

Figure 2.  Hypothermic effects of Baccharis uncinella essential oils (BU-PR and BU-SC, 50 and 100 mg/kg i.p.). Pentobarbital 50 mg/kg was used as positive control. * = p < 0.05; ** = p < 0.01 vs. control. ANOVA/SNK.

Figure 3.  Effects of Baccharis uncinella essential oils (BU-PR and BU-SC, 50 and 100 mg/kg, i.p.) on spontaneous locomotor activity. Each column represents the mean ± S.E.M. (n = 8–10). ** = p < 0.01 vs. control. ANOVA/SNK.