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Research Article

Anti-proliferative and matrix metalloproteinase-2 inhibition of Longkong (Lansium domesticum) extracts on human mouth epidermal carcinoma

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Pages 1311-1320 | Received 17 Jan 2013, Accepted 23 Mar 2013, Published online: 13 Jun 2013

Figures & data

Table 1. Comparison of the percentage yields of the 85 extracts from 8 parts of Longkong prepared by water, methanol and chloroform with cold and hot processes from the Northern and Eastern region of Thailand.

Table 2. Total phenolic and flavonoid contents of the 85 extracts from 8 parts of Longkong.

Table 3. Antioxidative activities of the 85 extracts from 8 parts of Longkong.

Table 4. Summations of the percentage yields, total phenolic content, total flavonoid content and antioxidative activities depending on the sources of Longkong, parts used, the extraction solvents and temperatures of the 85 extracts.

Figure 1. MMP-2 inhibition of the two selected Longkong extracts in comparing to the standard anticancer drugs on KB cells. NYFCC: Cold chloroform young fruit extracts from the Northern region and NYFCH: Hot chloroform young fruit extracts from the Northern region. *Significant difference (p < 0.05) in comparing to all standard anticancer drugs. †Significant difference (p < 0.05) in comparing to all standard anticancer drugs, except cisplatin. χSignificant difference (p < 0.05) in comparing to all standard anticancer drugs, except fluorouracil.

Figure 1. MMP-2 inhibition of the two selected Longkong extracts in comparing to the standard anticancer drugs on KB cells. NYFCC: Cold chloroform young fruit extracts from the Northern region and NYFCH: Hot chloroform young fruit extracts from the Northern region. *Significant difference (p < 0.05) in comparing to all standard anticancer drugs. †Significant difference (p < 0.05) in comparing to all standard anticancer drugs, except cisplatin. χSignificant difference (p < 0.05) in comparing to all standard anticancer drugs, except fluorouracil.

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