Figures & data
Figure 1. Enoxaparin and onion extract inhibited proliferation of fibroblast cells. Thymidine assay was used to measure DNA synthesis in human fibroblasts cultured for 48 h in response to vehicle control (control), different concentrations of enoxaparin (E), onion extract (O) and combinations of enoxaparin and onion extract. All assays were performed in triplicate in the culture of fibroblast cell line. Data are presented as a mean 3H-thymidine incorporation ± SD. *p < 0.0001 compared with untreated cells.
Figure 2. Effect of enoxaparin and onion extract on β1 integrin expression in human fibroblasts. The figure illustrates flow cytometry differences of mean fluorescence intensity ± SD of triplicate values. Cells for the experiments were cultured for 48 h in response to different concentrations of enoxaparin (E), onion extract (O) and combinations of onion extract and enoxaparin or vehicle medium (control). *p < 0.05 compared with untreated cells.
Figure 3. Effect of enoxaparin and onion extract on apoptosis in the culture of human fibroblasts. Cells were stimulated for 48 h with different concentrations of enoxaparin (E), onion extract (O) and combinations of enoxaparin and onion extract. The results are presented as mean rate of apoptosis representing early (FITC-Annexin V positive and PI negative) and late apoptotic cells (positive for FITC-Annexin V binding and for PI uptake) ± SD (n = 3 for each group). *p < 0.05.
