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Research Article

Folate-modified doxorubicin-loaded nanoparticles for tumor-targeted therapy

, , , &
Pages 978-982 | Received 14 Sep 2013, Accepted 09 Dec 2013, Published online: 14 Jul 2014

Figures & data

Figure 1. Preparation and modification of NPs/DOX complexes.

Figure 1. Preparation and modification of NPs/DOX complexes.

Figure 2. Optimization of the modification ratios of FA–PEG–PE to NPs/DOX.

Figure 2. Optimization of the modification ratios of FA–PEG–PE to NPs/DOX.

Table 1. Particle size, zeta potential, and gene loading quantity of different vectors.

Figure 3. The in vitro release profiles of FA-NPs/DOX and NPs/DOX.

Figure 3. The in vitro release profiles of FA-NPs/DOX and NPs/DOX.

Figure 4. In vitro cytotoxicity evaluation of FA-NPs and NPs.

Figure 4. In vitro cytotoxicity evaluation of FA-NPs and NPs.

Figure 5. The tumor growth curves of FA-NPs/DOX, NPs/DOX, NPs, and free DOX.

Figure 5. The tumor growth curves of FA-NPs/DOX, NPs/DOX, NPs, and free DOX.

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