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Original Article

Development of piperic acid derivatives from Piper nigrum as UV protection agents

Piyapong ChoochanaFaculty of Oriental Medicine, Rangsit University, Pathumthani, Thailand,

Jirapan MoungjaroenDepartment of Cosmetic Raw Material Suppliers, Numsiang International Co. Ltd., Bangkok, Thailand,

Nathjanan JongkonDepartment of Social and Applied Science, College of Industrial Technology, King Mongkut's University of Technology North Bangkok, Bangkok, Thailand, and

Wandee GritsanapanDepartment of Pharmacognosy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand

Prasan TangyuenyongwatanaFaculty of Oriental Medicine, Rangsit University, Pathumthani, Thailand, Correspondence[email protected]

Figures & data

Figure 1. Esterification of piperic acid with alcohols using Steglich reaction.

Table 1. UV absorption data of piperic acid derivatives in methanol.

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Table 2. The SPF values of the piperic acid derivatives (5% w/w) o/w emulsion.

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Figure 2. Structure of isopropyl piperate showed intra-molecular hydrogen bond.

Table 3. Molecular labeling and structural geometries of piperates compounds^a.

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Figure 3. The electron density distribution of piperate derivatives.

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Development of piperic acid derivatives from Piper nigrum as UV protection agents

Table 1. UV absorption data of piperic acid derivatives in methanol.

Table 2. The SPF values of the piperic acid derivatives (5% w/w) o/w emulsion.

Table 3. Molecular labeling and structural geometries of piperates compounds^a.

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Development of piperic acid derivatives from Piper nigrum as UV protection agents

Figures & data

Table 1. UV absorption data of piperic acid derivatives in methanol.

Table 2. The SPF values of the piperic acid derivatives (5% w/w) o/w emulsion.

Table 3. Molecular labeling and structural geometries of piperates compoundsa.

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Table 3. Molecular labeling and structural geometries of piperates compounds^a.