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Original Article

Luffa cylindrica suppresses development of Dermatophagoides farinae-induced atopic dermatitis-like skin lesions in Nc/Nga mice

, , , , , & show all
Pages 555-562 | Received 21 Nov 2013, Accepted 03 Jun 2014, Published online: 20 Oct 2014

Figures & data

Figure 1. Luffa cylindrica extract (LC) inhibited the production of PGE2 (A) and histamine (B) in LPS-stimulated RAW 264.7 and PMA- and A23187-treated HMC-1 cells, respectively. ##p < 0.01 compared with non-stimulated cells. *p < 0.05 and **p < 0.01 compared with stimulated cells, respectively.

Figure 1. Luffa cylindrica extract (LC) inhibited the production of PGE2 (A) and histamine (B) in LPS-stimulated RAW 264.7 and PMA- and A23187-treated HMC-1 cells, respectively. ##p < 0.01 compared with non-stimulated cells. *p < 0.05 and **p < 0.01 compared with stimulated cells, respectively.

Figure 2. Luffa cylindrica extract (LC) inhibited releases of TARC and RANTES, not MDC in TNF-α and IFN-γ-stimulated HaCaT cells. ##p < 0.01 compared with non-stimulated cells. *p < 0.05 and **p < 0.01 compared with stimulated cells, respectively.

Figure 2. Luffa cylindrica extract (LC) inhibited releases of TARC and RANTES, not MDC in TNF-α and IFN-γ-stimulated HaCaT cells. ##p < 0.01 compared with non-stimulated cells. *p < 0.05 and **p < 0.01 compared with stimulated cells, respectively.

Figure 4. The plasma levels of histamine (A) and IgE (B) in Nc/Nga mice. ## p < 0.01 compared with the normal group. *p < 0.05 compared with the D. farinae-sensitized group (control).

Figure 4. The plasma levels of histamine (A) and IgE (B) in Nc/Nga mice. ## p < 0.01 compared with the normal group. *p < 0.05 compared with the D. farinae-sensitized group (control).