Antioxidant and α-glucosidase inhibitory activities of Achillea tenorii

Figures & data

Figure 1. Identified compounds of polar fraction.

Table 1. Antioxidant activity of A. tenorii hydroalcoholic extract was measured with ABTS, DPPH, and FRAP-FZ tests and expressed in IC₅₀ values (µg/mL) or FRAP unit, which represent the sample amount which produces 100 µM Fe²⁺ and total antioxidant capacity (TAC) expressed in mmol Tr eq/g of extract.

ABTS		DPPH		FRAP-FZ
IC50	TAC	IC50	TAC	FRAP unit	TAC
22.49 ± 2.01	1.50	31.41 ± 3.13	0.71	21.56 ± 1.51	0.53

Figure 2. IC₅₀ plot of α-glucosidase inhibition calculated using 2 mM p-NG and expressed in µg/mL.

Figure 3. α-Glucosidase inhibition of chlorogenic acid, luteolin, and Achillea tenorii extract expressed in 1/IC₅₀ (mg⁻¹× mL).

Figure 4. Lineweaver–Burk plot of α-glucosidase and p-NPG, without (▪) and with (▴) Achilea tenorii extract at the IC₅₀ concentration.

Table 2. Kinetic parameters of f α-glucosidase and p-NPG without (negative control) and with Achilea tenorii extract at the IC₅₀ concentration (32 µg/mL). K_m was expressed in mM and v_max in nKat (nmol/s).

	Negative control	A. tenorii treated
Km (mM)	0.37	0.021
vmax (nKat)	0.56	0.028