Figures & data
Figure 1. Effects of isolated fractions on rabbit conjunctival edema. (A) Control, (B) n-BuOH, (C) PE, (D) CH2Cl2, (E) water, (F) SUPs, and (G) SEDs.
Figure 2. Effects of isolated fractions on NO release from macrophages. Results are reported as mean ± SEM (n = 6). *p < 0.01, compared with the control.
Figure 3. Chemical structures of compounds 1–4. 1: EsB; 2: EsA; 3: EsF; 4: EsC.
Figure 4. Dose–response curves describing the effects of esculentosides on the release of NO, TNF-α, and IL-1β from macrophages. (A) NO; (B) TNF-α; (C) IL-1β. Results are reported as mean ± SEM (n = 6). *p < 0.01, compared with the control.
Figure 5. Time–response curve describing the effects of esculentosides on the release of NO, TNF-α, and IL-1β from macrophages. (A) NO; (B) TNF-α; (C) IL-1β. Results are reported as mean ± SEM (n = 6).
Figure 6. Effects of esculentosides, n-BuOH fraction, and SUPs fraction on the release of NO, TNF-α, and IL-1β from macrophages. EsC functioned more effectively than EsF did and similar to the esculentoside mixture did. The proinflammatory effect of EsC was equivalent to those of n-BuOH and SUPs fractions. Results are reported as mean ± SEM (n = 6). *p < 0.01, compared with the control.
Figure 7. Irritating effects of esculentosides on rabbit conjunctival edema. (A) Control; (B) EsA; (C) EsB; (D) EsC; (E) EsF; (F) MIX.
