Figures & data
Figure 1. HPLC chromatographic profile of HEA. (A) Rutin standard (RT 16.90 min); (B) EtOAc fraction of HEA (10 mg/mL). (1) Rutin and (2) kaempferol-3-O-glucuronide (according to Victório et al., Citation2010).
![Figure 1. HPLC chromatographic profile of HEA. (A) Rutin standard (RT 16.90 min); (B) EtOAc fraction of HEA (10 mg/mL). (1) Rutin and (2) kaempferol-3-O-glucuronide (according to Victório et al., Citation2010).](/cms/asset/050e67ee-d44c-4fd5-8766-33bcc5a0aec9/iphb_a_1025287_f0001_c.jpg)
Figure 2. Effects of AMPT (100 mg/kg, i.p.) on the HEA (800 mg/kg, p.o.) actions in the TST. Each column represents the mean ± SEM. N = 8–10. *p < 0.01 × saline–saline. Two-way ANOVA followed by Tukey’s post hoc test.
![Figure 2. Effects of AMPT (100 mg/kg, i.p.) on the HEA (800 mg/kg, p.o.) actions in the TST. Each column represents the mean ± SEM. N = 8–10. *p < 0.01 × saline–saline. Two-way ANOVA followed by Tukey’s post hoc test.](/cms/asset/5e5fced9-d0ed-49d3-bfcd-c44a9c01ba5c/iphb_a_1025287_f0002_b.jpg)
Figure 3. Effects of PCPA (100 mg/kg, i.p.) on the HEA (800 mg/kg, p.o.) actions in the TST. Each column represents the mean ± SEM. N = 8–10. *p < 0.01 × saline–saline. Two-way ANOVA followed by Tukey’s post hoc test.
![Figure 3. Effects of PCPA (100 mg/kg, i.p.) on the HEA (800 mg/kg, p.o.) actions in the TST. Each column represents the mean ± SEM. N = 8–10. *p < 0.01 × saline–saline. Two-way ANOVA followed by Tukey’s post hoc test.](/cms/asset/3ab4cf8d-6c6d-4527-aff7-f3935ed533cd/iphb_a_1025287_f0003_b.jpg)
Figure 4. Effects of NBQX (10 mg/kg, i.p.) on the HEA (800 mg/kg, p.o.) actions in the TST. Each column represents the mean ± SEM. N = 8–10. *p < 0.01 × saline–saline. Two-way ANOVA followed by Tukey’s post hoc test.
![Figure 4. Effects of NBQX (10 mg/kg, i.p.) on the HEA (800 mg/kg, p.o.) actions in the TST. Each column represents the mean ± SEM. N = 8–10. *p < 0.01 × saline–saline. Two-way ANOVA followed by Tukey’s post hoc test.](/cms/asset/b864daf8-8f8c-4b12-ae26-25702de4596e/iphb_a_1025287_f0004_b.jpg)