Relative survival after CABG surgery is poorer in women and in patients younger than 70 years at surgery

Figures & data

Figure 1. Survival of all CABG patients (black continuous) with 95% confidence intervals (grey). Expected survival (black fragmented). X-axis represents years after surgery.

Figure 2. Relative survival curves for men and women, respectively black and grey with confidence intervals. Y-value “1” represents equal to expected survival. X-axis represents years after surgery.

Figure 3. Male relative survival <70 (black), and female <(70 grey) with 95% C.I. X-axis represents years after surgery.

Table I. Perioperative variables for total CABG (n = 6696) population.

	Males (n = 5363)	Females (n = 1336)	P-value
ITA-usage	91.4%	90.1%	=0.201
Number venous anast	2.58	2.43	<0.0001
Flow ITA (ml/min)	29.0	22.4	<0.0001
Extracorporeal circulation (min)	84.16	83.03	0.28
Aorta crossclamping time (min)	50.4	49.1	0.044

ITA, Arteria thoracica interna.

Table II. Preoperative variables in subgroups (n = 52, n = 55).

	DOY (n = 52)	AOY (n = 54)	p-value/OR (95%)
Age (years)	68.3	64.9	p = 0.212
Body surface (m^2)	1.72	1.71	p = 0.822
Ejection fraction (%)	53.5	65.4	p = < 0.001
eGFR	59.1	72.8	p = < 0.001
Hypercholesterolemia	23/52 = 44.2%	31/54 = 57.4%	OR = 0.59(0.3–1.3)
Diabetes non insulin	4/50 = 8%	3/54 = 5.6%	OR = 1.47(0.32–6.78)
Diabetes insulin	6/50 = 12%	3/54 = 5.6%	OR = 2.24(0.57–8.75)
Diabetes total	10/50 = 20%	6/54 = 11.2%	OR = 0.5(0.17–1.50)
Myocardial infarction
>21 days prior to CABG	27/52 = 51.9%	19/54 = 35.2%	OR = 1.96(0.91–4.22)
<21 days prior to CABG	10/52 = 19.2%	7/54 = 13.0%	OR = 1.58(0.56–4.45)
One-vessel disease	2/51 = 3.9%	5/54 = 9.3%	OR = 0.31(0.08–1.24)
Two-vessel disease	7/51 = 13.7%	15/54 = 27.8%	OR = 0.43(0.17–1.10)
Three-vessel disease	42/51 = 82.3%	34/54 = 63.0%	OR = 2.61(1.12–6.13)
Disseminated vasc. dis	10/50 = 20.0%	13/54 = 24.1%	OR = 0.79(0.31–2.00)
COLS Gold I	5/52 = 9.6%	3/54 = 5.6%	OR = 1.77(0.42–7.47)
COLS Gold II	1/52 = 1.9%	1/54 = 1.9%	OR = 1.04(0.06–16.84)
COLS Gold III	0	0
COLS Gold IV	0	0
LITA	40/48 = 83.3%	47/54 = 87%	OR = 0.75(0.25–2.23)
Previous PCI	3/52 = 5.8%	6/54 = 11.1%	OR = 0.49(0.12–2.07)
LMS	27/52 = 51.9%	10/53 = 18.7%	OR = 4.20(1.89–9.31)

AOY, alive after one year after CABG; DWOY, death within one year after CABG; eGFR, estimated glomerular filtration ratio; ITA, internal thoracic artery; LMS, left main stenosis; Previous PCI, percutan coronary intervention prior to coronary surgery.