Men born in 1913 followed to age 100 years

Figures & data

Figure 1. Survival from age 80 to 100 years among non-smokers (full line) and smokers (broken line).

Table I. Significant variables at multivariable Poisson analysis during follow-up from 50 to 100 years.

Variable	Beta	Standard error	Hazard ratio	p-value
Constant	− 9.4421	0.8183
Time since age 50	0.0859	0.0101	1.09 (1.07–1.11)	0.0000
Smoking	− 0.5802	0.0918	0.56 (0.47–0.67)	0.0000
High social class	0.0031	0.0009	1.00 (1.00–1.00)	0.0005
Maximum work capacity	0.0003	0.0000	1.00 (1.00–1.00)	0.0000
Mothers' age at death	− 0.0274	0.0112	0.97 (0.95–0.99)	0.0145
Mothers' age at death Time since age 50 in the present men	− 0.0003	0.0001	1.00 (1.00–1.00)	0.0194

Table II. Findings at examination and laboratory tests in seven men aged 100 years.

Man no.	326	528	179	664	730	844	988
Smoker	No	No	No	No	No	No	No
Blood pressure, mmHg	182/82	140/60	120/82	124/80	140/80	130/70	170/74
S-cholesterol, mmol/L	5.4	2.8	5.8	5.4	5.2	5.2	4.2
S-trigycerides, mmol/L	0.9	2.0	1.4	3.4	1.0	1.7	2.2
s-HDL-cholesterol, mmol/L	1.8	1.1	1.7	1.2	1.7	1.0	1.3
s-LDL-cholesterol, mmol/L	3.3	1.1	3.6	1.6	3.4	3.6	2.2
Non-fasting glucose, mmol/L	6.1	7.4	5.9	9.7	5.2	6.0	13.3*

*Known diabetes.

Table III. Biomarkers in seven men aged 100 years.

Man No	326	528	179	664	730	844	988
Haemoglobin, g/L (Ref. values 134–170)	120	106	134	119	112	131	119
hsTnT, ng/L (Ref. value < 14)	28.4	15.0	43.8	32.4	20.5	39.4	30.0
NTproBNP, ng/L (Ref. value < 400)	1070	232	1560	551	598	1190	187
hsCRP, mg/L (Ref. value < 2.0)	11.0	4.5	6.4	1.3	6.9	3.9	7.9

hsTnT, High sensitive troponin T; NTproBNP, N-Terminal pro brain natriuretic peptide; hsCRP, High sensitive C-reactive protein.

Table IV. Findings at echocardiography in seven men aged 100 years.

Man no.	326	528	179	664	730	844	988
Ejection fraction, %	> 50	> 50	45–50	> 50	> 50	> 50	> 50
LVEDD, mm	42	43	38	52	36	42	44
IVSEDD, mm	13	10	11	12	11	11	8
Aortic gradient, mmHg	< 16	< 16	< 16	< 16	< 16	< 16	24
Aortic insufficiency, (/4)	1	1	0	1	0	1	0
Mitral insufficiency, (/4)	1	0	0.5	0	0	0	0
Tricuspid insufficiency, (/4)	1	1	1	0.5	0.5	2	0.5
TI gradient, mmHg	20	–	–	18	–	25	–
Pericardial effusion, (+/−)	–	–	–	–	–	–	–
Pericardial calcification, (+/−)	–	–	–	–	–	–	–
Aorta ascend. diameter, mm	27	32	39	29	30	26	26
Aortic sinus, mm	35	34	36	29	36	30	28
Rhythm	SR	SR	Atr. fibril.	SR	SR	SR	SR

SR, sinus rhythm; LVEDD, left ventricular end diastolic diameter; IVSEDD, Interventricular septum end diastolic diameter; TI, tricuspid regurgitation gradient.