Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase

Figures & data

Figure 1.  Chemical structures of oxime K027 and obidoxime.

Table 1.  Reactivation of nerve agent- and pesticide-inhibited AChE by oxime K027.

OP inhibitor	Reactivation (%)
	10^−5 M	10^−3 M
Tabun	1	11
Sarin	2	22
Cyclosarin	0	0
Soman	0	6
VX	7	70
Russian VX	3	39
Paraoxon	21	59
DDVP	5	26
Methylchlorpyrifos	23	45