Figure 1. Structures of CB1/CB2 agents.
Scheme 1. Reagents and conditions: (A) piperidine/acetic acid, toluene/reflux, (B) ethyl chloroformate /triethylamine, H-ZR (where Z refer to nitrogen or oxygen and R alkyl or aryl), stirring at rt.
Scheme 2. Reagents and conditions: (A) Acetic acid, stirring at rt, (B) ethyl chloroformate/triethylamine, at 10 °C then H-ZR and stirring at rt.
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