Figures & data
Scheme 1. Schematic representation of the synthetic route A, B and C.
Scheme 2. General synthesis of compounds 1-18.
Scheme 3. Numeration and tautomers of kojic acid in basic medium.
Table 1. Physicochemical parameters of the synthesized compounds.
Table 2. Anticonvulsant and neurotoxicity screening data of the synthesized compounds.
Table 3. Screening for antimicrobial activity against Gram positive bacteria and Mycobacterium (MIC in µg/mL).
Table 4. Screening for antimicrobial activity against Gram negative bacteria (MIC in µg/mL).
Table 5. Screening for antifungal activity of the compounds (MIC in µg/mL).
Figure 1. Phenyl and benzylpiperazine derivatives of Mannich bases of chlorokojic acid.
