Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors

Alaa A-M. Abdel-AzizDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia, ;Department of Medicinal Chemistry, Faculty of Pharmacy, University of Mansoura, Mansoura, Egypt, Correspondence[email protected]

Adel S. El-AzabDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia, ;Department of Organic Chemistry, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt,

Deniz EkinciDepartment of Agricultural Biotechnology, Faculty of Agriculture, Ondokuz Mayıs University, Samsun, Turkey,

Murat ŞentürkChemistry Department, Science and Art Faculty, Ağrı İbrahim Çeçen University, Ağrı, Turkey, and

Claudiu T. SupuranNeurofarba Department, University of Florence, Florence, ItalyCorrespondence[email protected]

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Figure 1. Structure of the tested compounds.

Table 1. hCA I and II inhibition data with compounds 1–10, by an esterase assay with 4-nitrophenylacetate as substrateCitation9.

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Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors

Table 1. hCA I and II inhibition data with compounds 1–10, by an esterase assay with 4-nitrophenylacetate as substrateCitation9.

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Investigation of arenesulfonyl-2-imidazolidinones as potent carbonic anhydrase inhibitors

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Table 1. hCA I and II inhibition data with compounds 1–10, by an esterase assay with 4-nitrophenylacetate as substrateCitation9.

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