Automatic CPAP Performance in Patients with Sleep Apnea Plus COPD

Figures & data

Figure 1.  Normal breathing during CPAP titration.

Figure 2.  Changes in pressure ≥2 cm H2O in reaction to apnea and hypopnea.

Figure 3.  Period of inadequate pressure increases. Increases in pressure from 8 cm H2O to 10 cmH2O.

Figure 4.  Absence of pressure increases in reaction to respiratory events.

Figure 5.  Air leaks. The arrow shows the beginning of the leak period.

Figure 6.  Pressure behaviour in to the face of erratic breathing periods when the patient is awake.

Table 1.  Baseline data of SAHS and SAHS plus COPD patients

	SAHS	SAHS plus COPD	p
Male/Female	7/3	10/0
Age (SD)	60 (12)	64 (8)	0.155
BMI (SD)	32.3 (4.3)	32.1 (6.2)	0.574
AHI (SD)	62.1 (34.4)	50.9 (37.5)	0.575
CT90 (SD)	31.2 (18.6)	28.5 (21.6)	0.483

*p-value < 0.05 is statistically significant.

Table 2.  CPAP performance in patients with SAHS and no co-morbidity and in patients with SAHS and COPD

	SAHS	SAHS plus COPD	p
N	10	10
Sleep efficiency (SD)	80.2 (11.5)	76.5 (12.1)	0.533
Arousal index (SD)	12.4 (6.1)	12.8 (5.9)	0.880
Residual AHI (SD)	6.3 (5.2)	5.1 (7.7)	0.517
Residual CT90% (SD)	1.3 (3.5)	13.9 (31.6)	<0.05
Periods of inadequate pressure increases (SD)	1.2 (1.5)	1.3 (1.2)	0.885
Periods of absence of pressure increases in the face of respiratory events (SD)	4.1 (5.4)	0.6 (0.7)	0.075
Periods of air leaks (SD)	1.3 (3.8)	13.9 (11.7)	0.005
Optimal pressure (SD)	9.1 (1.4)	9.0 (1.9)	0.853

*p-value < 0.05 is statistically significant.

Table 3.  Mild in severe leaks in patients with SAHS without co-morbidity and in patients with SAHS and COPD

	SAHS	SAHS and COPD		p
		Mild leaks (<30 min)	Severe leaks (>30 min)
Sleep efficiency% (SD)	79.9 (11.3)	76.8 (12.9)	76.1 (12.8)	Ns
Arousals index (SD)	12.4 (6.1)	12.8 (4.97)	12.8 (7.29)	Ns
Residual AHI (SD)	6.3 (5.2)	1.2 (0.84)	9 (9.67)	0.056
Residual CT90% (SD)	1.3 (3.5)	0.2 (0.45)	27.6 (42.1)	0.02

*p-value < 0.05 is statistically significant.