Figures & data
Figure 1. Protocol for MPT showing timing and sequence of metronome pacing.
Table 1. Baseline characteristics of the subjects
Figure 2. Time course and degree of dynamic hyperinflation produced by MPT. Columns represent mean inspiratory capacity (% predicted) ± SEM for each condition of testing. There is a graded decline in inspiratory capacity with increasing respiratory rates for both I:E ratios. *P < 0.05 for same I:E ratio compared to baseline. †P < 0.05 versus same respiratory rate at different I:E ratio.
Table 2. Change in inspiratory capacity (∆IC) for each condition of MPT
Figure 3. Degree of dynamic hyperinflation produced by symptom-limited cycle ergometry.
Figure 4. Degree of dynamic hyperinflation produced by metronome-paced tachypnea and exercise testing.
Figure 5. Comparison between DH induced during MPT and XT for two separate patients. Patient 1 demonstrates DH during both MPT and XT; a respiratory rate above 40 breaths/min is achieved during XT. Patient 2 demonstrates DH during MPT but not during XT, which is terminated prematurely due to exhaustion; the highest respiratory frequency reached during XT is only approximately 30 breaths/minute.
Figure 6. Bland-Altman comparison of DH during MPT and XT. Bland and Altman method plotting the nett difference in decrease in IC versus mean decrease in IC following MPT and exercise testing. There was a bias for a greater decrease in IC following MPT.
