High-resolution optical coherence tomography correlates in ischemic radiation retinopathy

Abstract

Purpose: To find the abnormalities in various retinal layers caused by radiation retinopathy using spectral domain optical coherence tomography (SD-OCT).

Methods: We report a case of radiation retinopathy that was imaged using SD-OCT Copernicus (Optopol, Zawiercie, Poland). Analysis and synthesis of the OCT image were done using information both at the fovea and 2.5 mm temporal to the fovea.

Results: The layers that were reduced in thickness included the inner plexiform layer (47 μm vs. 74 μm), the inner nuclear layer (17 μm vs. 48 μm), and the outer plexiform layer (25 μm vs. 45 μm), whereas the layers with comparable thickness included the nerve fiber layer (24 μm vs. 25 μm), the outer nuclear layer (42 μm vs. 43 μm), the outer segment–inner segment junction (52 μm vs. 54 μm), and the retinal pigment epithelium (RPE) choriocapillaris layer (30 μm vs. 28 μm).

Conclusion: This report suggests that the radiation-induced damage was confined to the inner layers of the retina. However, secondary outer retinal layer changes may also occur, as suggested by functional derangements.

Keywords::

• Radiation retinopathy
• optical coherence tomography
• histopathologic correlate
• retinal thickness

Acknowledgments

Declaration of interest

The authors declare that there are no conflicts of interest.