The relation between schizotypy and early attention to rejecting interactions: The influence of neuroticism

Figures & data

Figure 1. Schematic representation of the affect processing task comprising scenes depicting social rejection, acceptance and neutral interactions.

Figure 2. Plot of the grand average waveform at midline frontal, midline parietal and right temporo-parietal sites from 200 ms pre-stimulus to 1-s post-stimulus during the affect processing task. The blue solid line depicts the waveform for rejection, red dotted line depicts the waveform for acceptance, and the green broken line depicts the waveform for neutral scenes.

Figure 3. (a) Plot of the rescaled configuration matrix loadings of the nine temporal PCA factors from 200 ms pre-stimulus baseline to 1-s post-stimulus onset during the affect processing task, and (b) the scalp-level maps of the spatial scores of temporal factor 9 (P200) and 2 (N300/P300). Only positive values (depicted in red in Figure 3b) denote the intensity of spatial mapping, since the scalp maps are based on matrix loadings.

Figure 4. Cortical source current density difference map depicting greater dorsal anterior cingulate P200 activation during rejection than neutral scenes.

Figure 5. Correlation between negative schizotypy and right middle occipital gyrus P200 current density (MNI co-ordinates 30, –80, 15) during rejection scenes.

Table I. Regression of P200/P300 amplitude during rejection scenes on schizotypy.

Included predictor variables	F (df)	β	R^2	P
(a) Predictors of positive schizotypy
Right parietal P200 (TF9-SF1)	6.614 (1,39)	–0.381	0.145	0.014
Excluded predictor variables
^†Midline occipital P200 (TF9-SF2)		0.010		0.947
^†Midline frontal N300 (TF2-SF1)		0.175		0.247
^†Midline parietal P300 (TF2-SF3)		0.192		0.215
^†Right temporo-parietal P300 (TF2-SF3)		0.051		0.737
(b) Predictors of negative schizotypy
Midline parietal P300 (TF2-SF2)	5.105 (1,39)	0.340	0.116	0.030
Excluded predictor variables
^†Right parietal P200 (TF9-SF1)		–0.192		0.222
^†Midline occipital P200 (TF9-SF2)		<0.001		0.999
^†Midline frontal N300 (TF2-SF1)		0.030		0.849
^†Right temporo-parietal P300 (TF2-SF3)		0.066		0.680

B, Standardised beta; TF, temporal factor; SF, spatial factor.

† Here, standardised beta is the size of the standardised regression weight if that variable had been entered into the model by itself in the next stage, and P is the significance level of R² change if that the variable had entered into the regression equation.

Table II. Hierarchical regression of schizotypy and neuroticism on P200/P300 activation during rejection scenes.

Predictor variables	F (df)	p1	R	R^2	F change	p2	R^2 change	β	p3	Partial r
(a) Regression of positive schizotypy and neuroticism on right parietal P200 amplitude
Step 1	6.614 (1,39)	0.014	0.381	0.145	–	–	–
Positive schizotypy								–0.381	0.014	–0.381
Step 2	3.399 (2,38)	0.044	0.390	0.152	0.302	0.586	0.007
Positive schizotypy								–0.333	0.061	–0.299
Neuroticism								–0.095	0.586	–0.089
(b) Regression of negative schizotypy and neuroticism on middle occipital P200 current density
Step 1	19.899 (1,39)	<0.001	0.581	0.338	–	–	–
Negative schizotypy								–0.581	<0.001	–0.581
Step 2	9.824 (2,38)	<0.001	0.584	0.341	0.172	0.681	0.003
Negative schizotypy								–0.620	<0.001	0.529
Neuroticism								–0.067	0.681	–0.067
(c) Regression of negative schizotypy and neuroticism on midline parietal P300 amplitude
Step 1	5.105 (1,39)	0.030	0.340	0.116	–	–	–
Negative schizotypy								0.340	0.030	0.340
Step 2	4.177 (2,38)	0.023	0.425	0.180	2.988	0.090	0.064
Negative schizotypy								0.160	0.381	0.142
Neuroticism								0.312	0.092	0.270

β, Standardised beta; p₁, P-value of F, p₂, P-value of F-change, p₃, P-value of standardised beta.

Figure 6. Scatterplot of midline parietal P300 amplitude during rejection scenes and negative schizotypy scores according to high, moderate and low neuroticism groups. The green dotted line represents the high neuroticism group, the red solid line represents the moderate neuroticism group, and the blue broken line represents the low neuroticism group. The circled data point indicates an outlier in the high neuroticism group.