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Original Article

Comparative modeling of exposure to airborne nanoparticles released by consumer spray products

Christian RiebelingDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, GermanyCorrespondence[email protected]

Andreas LuchDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany

Mario Enrico GötzDepartment of Chemical and Product Safety, German Federal Institute for Risk Assessment (BfR), Berlin, Germany

Figures & data

Table 1. Nanomaterial parameters used in the MPPD calculations (as requested in the MPPD menu Input Data > Particle Properties).

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Table 2. Calculation of the deposition per breath for different diameters of silver NPs using MPPD and the exposure scenario “consumer upright”.

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Table 3. Calculated mass and particle number corresponding to the human NOEL_hyp derived by the overload volume of 1.5 µm³ per alveolar macrophage for different NPs.

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Figure 1. Relative deposition of silver (% external exposure) against particle diameter [µm] for the four exposure scenarios as calculated by MPPD. Note that the exposure dose has no influence on the relative distribution in MPPD v2.11. (A) Consumer, upright; (B) consumer, leaning forward; (C) bystander, child; (D) infant, lying. Total deposition (black), head (middle gray, blue), conducting airways (light gray, yellow), alveolar region (dark gray, red).

Table 4. Mass deposition of NPs per alveolar macrophage upon exposure to 1.10⁶ particles/cm³ for 5 min.

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Table 5. Mass deposition of NPs per alveolar macrophage upon exposure to 1·10⁸ particles/cm³ of agglomerates of 250 nm CMD, GSD = 2.0, of the density of the loosest packing for 5 min.

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Supplementary Materials

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Comparative modeling of exposure to airborne nanoparticles released by consumer spray products

Table 1. Nanomaterial parameters used in the MPPD calculations (as requested in the MPPD menu Input Data > Particle Properties).

Table 2. Calculation of the deposition per breath for different diameters of silver NPs using MPPD and the exposure scenario “consumer upright”.

Table 3. Calculated mass and particle number corresponding to the human NOEL_hyp derived by the overload volume of 1.5 µm³ per alveolar macrophage for different NPs.

Table 4. Mass deposition of NPs per alveolar macrophage upon exposure to 1.10⁶ particles/cm³ for 5 min.

Table 5. Mass deposition of NPs per alveolar macrophage upon exposure to 1·10⁸ particles/cm³ of agglomerates of 250 nm CMD, GSD = 2.0, of the density of the loosest packing for 5 min.

Supplementary Materials

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Comparative modeling of exposure to airborne nanoparticles released by consumer spray products

Figures & data

Table 1. Nanomaterial parameters used in the MPPD calculations (as requested in the MPPD menu Input Data > Particle Properties).

Table 2. Calculation of the deposition per breath for different diameters of silver NPs using MPPD and the exposure scenario “consumer upright”.

Table 3. Calculated mass and particle number corresponding to the human NOELhyp derived by the overload volume of 1.5 µm3 per alveolar macrophage for different NPs.

Table 4. Mass deposition of NPs per alveolar macrophage upon exposure to 1.106 particles/cm3 for 5 min.

Table 5. Mass deposition of NPs per alveolar macrophage upon exposure to 1·108 particles/cm3 of agglomerates of 250 nm CMD, GSD = 2.0, of the density of the loosest packing for 5 min.

Supplementary Materials

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Table 3. Calculated mass and particle number corresponding to the human NOEL_hyp derived by the overload volume of 1.5 µm³ per alveolar macrophage for different NPs.

Table 4. Mass deposition of NPs per alveolar macrophage upon exposure to 1.10⁶ particles/cm³ for 5 min.

Table 5. Mass deposition of NPs per alveolar macrophage upon exposure to 1·10⁸ particles/cm³ of agglomerates of 250 nm CMD, GSD = 2.0, of the density of the loosest packing for 5 min.