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Basic research

Denervation impairs bone regeneration during distraction osteogenesis in rabbit tibia lengthening

, , , , &
Pages 406-410 | Received 15 Sep 2011, Accepted 14 Apr 2012, Published online: 10 Aug 2012

Figures & data

Figure 1. Suspension of the operative hind limb in a custom-designed sling.

Figure 1. Suspension of the operative hind limb in a custom-designed sling.

Figure 2. Radiographs of the distracted tibias taken from group R (A) and group I (B). There was significantly higher radio-density in the distracted callus in group I.

Figure 2. Radiographs of the distracted tibias taken from group R (A) and group I (B). There was significantly higher radio-density in the distracted callus in group I.

Figure 3. Micro-CT images of the distraction callus. Group R (A) had significantly thinner cortical bone and less bone formation than group I (B).

Figure 3. Micro-CT images of the distraction callus. Group R (A) had significantly thinner cortical bone and less bone formation than group I (B).

Figure 4. Parameters of distracted callus in both groups were analyzed by micro-CT. a p < 0.05 vs. group R. b p > 0.05 vs. group R.

Figure 4. Parameters of distracted callus in both groups were analyzed by micro-CT. a p < 0.05 vs. group R. b p > 0.05 vs. group R.

Figure 5. Longitudinal sections of the distraction callus. There was significantly less mature bone and significantly thinner cortical bone in group R (A) than in group I (B).

Figure 5. Longitudinal sections of the distraction callus. There was significantly less mature bone and significantly thinner cortical bone in group R (A) than in group I (B).